Sectorial Operational Programme ”Increasing Economic Competitiveness“
“Investments for your future!”
CENTER FOR RESEARCH AND DEVELOPMENT OF THE MORPHOLOGICAL AND GENETIC STUDYIES OF MALIGNANT PATHOLOGY
Project co-financed by the European Regional Development Fund

Molecular Biology Platform

Laboratory:

  • Molecular Genetics Laboratory
  • Tissue and Tumor Bank

Activities: Nucleic acid extraction and qualitative / quantitative evaluation

  • Amplification of DNA sequences;
  • Quantitative / semi-quantitative techniques for nucleic acid analysis by Real-time PCR;
  •  Assessment of methylation status and loss of heterozygous state (LOH);
  •  Molecular analysis of gene expression by reverse-transcription techniques;
  •  Evaluation of gene expression by Microarray techniques;
  •  Analysis of gene mutations / polymorphisms through:
  1. techniques using restriction enzymes - PCR-RFLP technique (Polymerase Chain reaction - Restriction Fragments Lenght Polymorphisms)
  2. SSCP technique (Single Strand Confirmation Polymorphism)
  3.  ARMS-PCR technique - PCR (Amplification-refractory mutation system - PCR)
  4. MLPA technique (Multiplex Ligation-Dependent Probe Amplification)
  5. DNA sequencing using SANGER methods
  6. Next Generation Sequencing techniques (NGS)<img alt="" data-cke-saved-src="http://cedmog.ro/files/photos/124_thumbnail.jpg" src="http://cedmog.ro/files/photos/124_thumbnail.jpg" "="">
For detailed information about other operational programs co-financed by the European Union please visit www.fonduri-ue.ro
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